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Description

Together, this dual mechanism enables our nanozyme-functionalized hydrogel to break the ROS-ferroptosis-inflammation feedback loop, thus effectively promoting structural and functional disc repair

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It drives the transition from proliferation to differentiation and increases the number and length of multinucleated myotubes in a dosedependent manner.The mechanism is mainly related to NNMT inhibition, restored NAD levels, and activation of the SIRT1PGC1 pathway

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